Stimulation of Bacterial Growth in Amniotic Fluid by Meconium and Its Inhibition according to Addition of Zinc / 대한주산의학회잡지

No abstract available.

Long-Term Effects of Oral Progesterone (Medroxyprogesterone Acetate) on the Level of Bone Mineral Density During Estrogen Replacement Therapy in Postmenopausal Women / 대한산부인과학회잡지

Estrogen replacement therapy is known to reduce the incidence of cardiovascular disease and osteoporosis in postmenopausal women. Estrogen has beneficial effect on bone density and adding progesterone to estrogen is known to have synergistic effect. However, the effect of progesterone on bone mineral density had not been precisely evaluated in Korean postmenopausal women. To evaluate the impacts of progesterone on bone mineral density during estrogen replacement therapy, we conducted the randomized 2-year trials of conjugated equine estrogen (Premarin(R) 0.625 mg/day) with or without cyclic progesterone(medroxyprogesterone acetate : MPA 10 mg/day for 12 days) in 105 postmenopausal women. Bone mineral density was measured in the lumbar vertebrae(L2-L4) using dual energy X-ray absorptiometry(DEXA) at the beginning of the treatment, 6 onths, 12 months and 24 months later, respectively. In Premarin only group, bone mineral density at 6 months and 12 months after treatment did not show significant difference from baseline value. But bone mineral density on 24 months after treatment showed significantly increased value(p value<0.05) than that of initial. In Premarin plus MPA group, bone mineral density at 12 months and 24 months after treatment showed significantly increased than baseline(p value<0.05). And compared with Premarin only group, Premarin plus MPA group showed significant increase in spinal bone density after 2 years treatment(p value<0.05). These results suggest that the addition of MPA in estrogen replacement therapy appears to increase in bone mineral density more than unopposed estrogen. Thus combination of estrogen and progesterone appeared to be effective long-term prophylactic treatment regimen upon postmenopausal bone loss.

A Case of benign Fibrous Histiocytoma in Ovary / 대한산부인과학회잡지

Benign fibrous histiocytoma is a tumor composed of a mixture of fibroblastic and histiocytic cells that are often arranged in a cartwheel or storiform pattern and accompanied by varying number of inflammatory cells, foam cells, and siderophages. Benign fibrous histiocytoma represents one of the common soft tissue tumors with most cases presenting in the skin. The common sites of incidence are the limbs, trunk, head, neck, and posterior peritoneal cavity: less commonly, these lesions arise in female reproductive organs. This report documents a case of benign fibrous histiocytoma arising in the ovary of 48 year-old female whose chief complaint was abdominal pain.